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T32 - Tzeng

NIH Ruth L. Kirschstein T32 Training Awards
Vascular Surgery Training Grant – Program Director: Edith Tzeng MD

National Institutes of Health (NIH) T32 institutional training grants support postdoctoral research training in specified areas of biomedical, behavioral and clinical research. These grants are also called National Research Service Awards (NRSA). The objective is to ensure that a diverse and highly trained workforce is available to assume leadership roles to advance the nation’s biomedical and clinical research agenda.

NIH T32 institutional training grants are awarded to an eligible institution, such as the University of Pittsburgh, to develop or enhance research training opportunities for individuals selected by the institution. The individual training programs are headed by a leader in the area of focus, and this individual is the named Program Director on the grant. Within the program, faculty members serve as mentors and lend their expertise and research opportunities to the trainees as part of the training plan.

The training program in the Division of Vascular Surgery is in its 3rd year and provides interdisciplinary laboratory training for up to six surgical residents or postdoctoral fellows with MD and/or PhD qualifications, and is funded by the National Institute of General Medical Sciences (NIGMS). Available projects include research studies relevant to endothelial and stem cell biology, nitric oxide biology and vascular and cutaneous wound healing. Read more about current projects on our Research page.

Name/Degree(s) Research Interests
Edith Tzeng, M.D. Translational studies of carbon monoxide and nitric oxide in intimal hyperplasia, angiogenesis, and wound healing, stem cell treatment of critical limb ischemia
Donald Baril, M.D. Comparative effectiveness and outcomes for endovascular interventions
Philip M. Bauer, Ph.D. Vascular injury; Pulmonary vascular biology
Timothy R. Billiar, M.D. Biological mechanisms involved in shock and sepsis and injury
Rabih Chaer, M.D. Endovascular interventions, venous interventions
Alex Chen, Ph.D. Cell and gene therapy on vascular injuries and regeneration
Bruce A. Freeman, Ph.D. Nitric oxide and nitrated fatty acids
Mark T. Gladwin, M.D. Pulmonary hypertension and pulmonary complications of sickle cell disease
David Hackam, M.D, Ph.D. Cell biology of the intestinal epithelium; innate immunity toll like receptor signaling; necrotizing enterocolitis
Johnny Huard, Ph.D. Expand the possiblities of tissue engineering by unlocking the potential of gene therapy and adult stem cell research and transferring research findings into the development of effective treatments for damaged or diseased tissues as they relate to the musculoskeletal system
Jeffrey Isenberg, M.D., Ph.D. Regulatory molecular events that act through the nitric oxide pathway to regulate blood flow and pressure as well as cardiac function in both the right and left sides of the circulation, mechanisms to enhance tissue blood flow, perfusion, and wound healing
Michael T. Lotze, M.D. Autophagy and necrotic cell death; cellular immunotherapy using cytokines, NK cells and dendritic cells; biology of inflammation and cancer
Michel Makaroun, M.D. Outcomes and comparative effectiveness, evaluation of vascular technology
Kacey Marra, Ph.D Adipose-derived stem cells, tissue engineering, nerve regeneration, soft tissue reconstruction, wound healing
Larissa Myaskovsky, Ph.D. Health services research and disparities in healthcare processes and outcomes
Bruce, Pitt Pulmonary vascular biology
Steven Reis, M.D.
Pathophysiological mechanisms for atherosclerosis, racial and gender disparities in CVD, clinical and translational research
Ulka Sachdev, M.D. Role of HMGB-1 and innate immune receptors in promoting antiogenesis after ischemic injury
Jason Sperry, M.D. M.P.H Prehospital Care Post Injury, Massive Transfusion, Trauma Induce Coagulophathy, Gender Based Outcome Differences Post-Injury, Endothelial Cell Activation and Coagulopathy
Flordeliza S. Villaneuva, M.D. Cardiovascular imaging
David A. Vorp, Ph.D. Mechanopatholobiological assessment of abdominal and thoracic aortic aneuyrsm, development of a human stem cell-based tissue engineered vascular graft, mechanical characterization of cerebral aneurysms
William Wagner, Ph.D. Cardiovascular tissue engineering and medical device biocompatibility and design
Simon Watkins, Ph.D. Optical imaging method and application to the study of basic cell biology and inflammation
Alan Wells, Ph.D. Mechanisms of cell migration, wound healing and organogenesis
Brian Zuckerbraun, M.D. Heme oxygenase/carbon monoxide in shock and inflammation; pulmonary hypertension; mitochondrial function


Trainees are expected to actively participate in research seminars, journal clubs, RCR training and laboratory meetings. Trainees are also encouraged to present their work at local and national meetings. Our training program provides trainees with the basic knowledge and required skills to enable them to function successfully as independent investigators. Financial support includes stipends, medical insurance, travel and other training-related expenses.

Eligibility: Individuals with a MD, MD/PhD or PhD must also be U.S. citizens or permanent residents. Applicants should be prepared to make a commitment of two to three years of training dedicated to full time research.

We seek to reflect our community with regard to gender, culture and life experiences, age, disability, race, ethnicity, geography, religion, sexual orientation and socioeconomic status. Diversity strengthens our institution by increasing talent and ensuring a fuller perspective. For further information on Diversity programs at the University of Pittsburgh please visit:

To apply: Please send a cover letter and resume to Kathy DiGiacomo either via email at digiacomok@upmc.edu or by mail at:

Kathy DiGiacomo
University of Pittsburgh
Department of Surgery Labs
NW607 MUH
3459 Fifth Avenue
Pittsburgh, PA  15213